From Seattle or Vancouver you'll be taking a nice drive up the Thompson River on highway 1 then 97 to the Cariboo.

Its about a 8 hour drive once you get to Vancouver. You can also access the Cariboo by any means through Kamloops, BC. Once you reach Quesnel, you'll drive through town and take a right onto Highway 26 and head to Wells while is about 70Km down the road. You can't miss it.